Flibanserin is a central nervous system medication used for the treatment of female sexual dysfunction. Dubbed the female Viagra, Flibanserin is a long overdue treatment option within a market where so many options exist for men. We will explain what it is used to treat and how it works in more detail shortly. Flibanserin is a generic medication, and this is also the name of the active ingredient.
It is sold under the brand name Addyi, however generic medications have exactly the same active ingredients and as pharmaceutical companies do not have the same initial development costs, they are a more affordable treatment option. This means you can buy the same medication without having to compromise on efficacy or safety. The medication was developed by the German pharmaceutical company Boehringer Ingelheim, initially as an anti-depressant.
When the company applied for the licence to be issued for this purpose however, it was rejected by the US Food and Drug Administration (FDA). Following this, the rights to the medication were sold to Sprout Pharmaceuticals, a relatively small and unknown company. They conducted further clinical trials researching the effects for the treatment of female sexual interest/arousal disorder (FSIAD) and applied for the medication to be licenced for this use.
Flibanserin was subsequently approved by the FDA; however, it has not yet been approved by Medications and Healthcare Products Regulatory Agency (MHRA) for use in Europe. There has been substantial campaigning over the years for a female sexual dysfunction medication and there was a lot of pressure for the licencing of Flibanserin, despite being a somewhat controversial medication.
Among other groups, Even The Score were strong advocates of the medication and they helped to ensure it was licenced for the treatment of FSIAD in pre-menopausal women. Although it is not yet available on the National Health Service (NHS), you can buy Flibanserin online in Europe from our pharmacy.
As we mentioned earlier, Flibanserin is used for the treatment of FSIAD, previously known as hypoactive sexual desire disorder (HSDD). This is the most common sexual dysfunction disorder affecting women around the world. In order to be diagnosed with FSIAD, you must experience the following symptoms:
As is clear from the above characteristics, the disorder is not simply a low sex drive. Women with the condition often state that their quality of life is affected and that they experience symptoms of low emotional and physical satisfaction. FSIAD is either diagnosed as generalised or situational, and it can be life-long or acquired. Generalised FSIAD means that the symptoms of the condition are always present, whereas situational FSIAD is due to specific people or circumstances.
Life-long FSIAD is less common than acquired FSIAD, with the former having always been present and the latter acquired later in life. Acquired FSIAD could develop as a result of a traumatic event or after an abusive relationship. If this is the case, most women find that some sort of psychological intervention such as counselling or cognitive behavioural therapy (CBT) is beneficial alongside medication such as Flibanserin. If you would like to buy Flibanserin and see whether it is useful for the management of your symptoms, you can do so from our Europe pharmacy without the need for a prescription.
Women and mens reproductive systems differ in terms of their hormones, which means they will have different levels of libido at different times. Womens hormone production increase and decrease in a cyclical manner, every 28 days on average. Oestrogen will increase over a period of two weeks, with progesterone increasing and decreasing over the next two weeks. The fluctuation in hormones is regulated by ovulation and menstruation. When oestrogen levels are higher women are typically more sexually active, and when progesterone levels are higher, women are usually less interested in sex.
This fluctuation in sex drive is completely normal and it is not the same as FSIAD. Men on the other hand, only have one predominant sexual hormone, namely testosterone, so their sex drive remains consistent throughout the month, which can make some women feel as if their lack of sexual desire at certain times of the month is a problem. A womans sex drive can also be affected by a variety of factors, including physical health issues such as endometriosis and polycystic ovary syndrome (PCOS), or mental health issues like depression and anxiety.
It is also worth mentioning that libido will usually decrease after the menopause, but it should not completely disappear. Flibanserin tablets are not suitable for post-menopausal women and are only licensed for pre-menopausal women diagnosed with FSIAD. One of the reasons that this diagnosis is controversial is that attitudes towards sex differs from country to country and some women are made to feel shamed or embarrassed because of their lower libido.
Although sex positivity is a huge step in the right direction for womens sexual liberty and freedom, there is very little recognition for those who do not want to have sex as often as others. Asexual men and women are the least represented in the LGBTQIA community and often misunderstood. As asexual people embrace their lack of sexual desire and it is not necessarily considered a disorder, the symptoms must also cause significant distress or relationship problems to be diagnosed. If you are experiencing the symptoms of FSIAD and it is causing you distress, you can buy Flibanserin online from our Europe pharmacy at affordable prices.
The Flibanserin mechanism of action works in a different way to the majority of male sexual dysfunction medications. As opposed to targeting the cardiovascular system by inhibiting the PDE-5 enzyme to relax smooth muscle and increase blood flow, Flibanserin tablets target the central nervous system. The active ingredient Flibanserin is known as a noradrenaline-dopamine disinhibitor (NDDI). It is an agonist for the noradrenergic and dopaminergic neuronal pathways and both an agonist and antagonist of the serotonergic pathway.
When the medication binds to the neuronal receptors, it stimulates the production of noradrenaline and dopamine neurotransmitters. In the case of serotonin neurotransmitters, although the medication binds to the 5-HT1A receptor and 5-HT2A receptor in equal amounts, certain factors mean that it has a higher affinity to the 5-HT2A receptor, which is inhibitory, resulting in the down regulation of serotonin. The exact mechanism of action for this higher affinity is not fully understood, but it is thoughts that the agonistic effects on the dopamine D4 receptor are partly responsible. Noradrenaline, dopamine, and serotonin are all involved in the regulation of reward processing activity, motivation, and feelings of happiness.
It is widely accepted in the scientific and medical communities that an imbalance in these neurotransmitters cause the symptoms of anxiety and depression. While and increase in all three neurotransmitters have shown to be beneficial in relieving the symptoms of depression, increased serotonin levels commonly result in reduced libido. Increased levels of noradrenaline and dopamine, however, have the opposite effect, which is what makes this medication effective.
The exact Flibanserin dosage can vary between individuals. Flibanserin 100mg is the usual starting dose however this can be altered if necessary. Lower doses may be indicated if you are generally more sensitive to medications or have a condition which is contraindicated. Flibanserin tablets need to be taken daily due to the mechanism of action. They target the central nervous system and the neuropathways and neurotransmitters that are affected means that taking the medication daily and stopping abruptly or taking tit intermittently can cause an imbalance leading to emotional dysregulation.
It may also result in the symptoms of FSIAD returning. The medication should be taken at night at it has sedative properties. Try to take it at roughly the same time at night, with a full glass of water ensuring not to crush or chew the medication. If you forget to take your usual dose, do not take an extra dose to make up for the missed one, just carry on taking it as usual from the following night.
As the medication takes a while to build up in your system, the Flibanserin benefits may take up to 4 weeks to achieve their full effects. If after 8 weeks you have not experienced any benefit, then you should not carry on taking the medication. If you discontinue treatment, make sure you gradually reduce your dose to reduce the risk of any side effects.
The Flibanserin effects should be maintained at a consistent level as the medication gradually builds up in your system, so the benefits are exerted continuously. So unlike male sexual dysfunction medications, you will not need to wait an hour before having sex, which allows you to be spontaneous. Having to plan when you have sex can really take the passion out of it so this can help with libido, giving you more confidence.
Before you buy Flibanserin it is important to be aware of any side effects. Most women find that they are mild to moderate and usually go away on their own. Some of the more common Flibanserin side effects include:
In rare cases, some women do experience syncope (fainting). If you suffer from regular hypotension, you should seek professional advice before taking this medication.
There are some contraindications to be aware of before you buy Flibanserin. Unfortunately, Flibanserin and alcohol do not mix well and drinking while taking it can cause your blood pressure to drop too low, causing you to lose consciousness. Clinical trials have shown that up to 17% of women who drank more than two glasses of wine (or equivalent) experienced syncope. So, you should only have a maximum of 2 glasses of wine and wait for at least 2 hours before taking your usual dose. It is important that you do not take your medication if you drink more than this and wait until the next night to continue your usual treatment.
Flibanserin has shown to cause a significant amount of weight loss in addition to treating the symptoms of FSIAD. Researchers initially thought this medication would cause weight gain as it is a serotonin a 5-HT2C antagonist. They compared their information to an FDA approved weight loss medication called Lorcaserin, which is a serotonin 5-HT2C receptor agonist, so has the opposite effect. These results suggest that the effects on the serotonin receptors are not responsible for the weight loss. Even though the exact mechanism of action of the medication is not fully understood, it is clear from the data that the weight loss is not a placebo effect. The participants who took part in the Flibanserin trials were not told to manage their diets, follow an exercise programme, there was no correlation with nausea and weight loss and they were not obese.
There are two female sexual dysfunction medications available for the treatment of FSIAD. Therefore, there is only one Flibanserin alternative, which is called Vyleesi. One benefit to Vyleesi is that it can be taken as-and-when necessary, as opposed to every day. It also does not interact with alcohol. It does, however, need to be administered by injection and it can only be used for a maximum of 8 times per month. It may also cause hyper pigmentation (darkening of the skin) which may become permanent.
Female sexual dysfunction medications are long overdue. Many women have stated that they feel unseen and let down by the pharmaceutical industry in terms of sexual health treatment options, especially when the burden of contraception lies primarily on them. It is not possible to buy Flibanserin over the counter or from your local sexual health centre, however, it is possible to buy Flibanserin online in Europe from our pharmacy.
Visit kamagratablets.com and place your order for the finest female sexual dysfunction medication today and wake up to a brighter tomorrow.
Last Reviewed: 10th July 2024
Next Review Due: August 2025
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